Real ChatGPT answer · index seedkNv6k0xML7YcompleteHealth and wellness · nutrition and dietscommercial

Which specific probiotic strains are clinically proven to repair intestinal permeability and how do popular over-the-counter supplements stack up against those clinical benchmarks

ChatGPTgpt-63 queries10/31/2026
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The searches the AI actually ran for this prompt.

SEED QUERY
Which specific probiotic strains are clinically proven to repair intestinal permeability and how do popular over-the-counter supplements stack up against those clinical benchmarks
3 real searches · 1 real-search pass
human clinical trials probiotic strains intestinal permeability lactulose mannitol randomized trial Lactobacillus rhamnosus GG Bifidobacterium infantis 35624Google ↗
OBSERVEDReason
probiotic intestinal barrier permeability clinical trial strain-specific evidence review 2024 2025Google ↗
OBSERVEDReason
probiotic supplements strain labels Align 35624 Culturelle LGG Florastor CNCM I-745 Visbiome strainsGoogle ↗
OBSERVEDComparison

Badge and edge weight = share of passes that produced the query. Hover a query for its intent and routing format.

Query classes

Google's semantic query class for every sub-query: what kind of answer each search is after, simulated vs real.

ChatGPT real searches (3)
Short factOther / navigationalComparison33%ConsequenceReason67%DefinitionInstructionYes / no

Classes come from the query-classifier (a local Laya model). 3 of 3 calls are low-confidence (under 50%) — hover a query in the table to see its confidence.

Searches and sources

ChatGPT3 real searches · gpt-6
human clinical trials probiotic strains intestinal permeability lactulose mannitol randomized trial Lactobacillus rhamnosus GG Bifidobacterium infantis 35624 Google ↗
probiotic intestinal barrier permeability clinical trial strain-specific evidence review 2024 2025 Google ↗
probiotic supplements strain labels Align 35624 Culturelle LGG Florastor CNCM I-745 Visbiome strains Google ↗
  1. Immune response and intestinal permeability in children with acute gastroenteritis treated with Lactobacillus rhamnosus GG: a randomized, double-blind, placebo-controlled trial · pubmed.ncbi.nlm.nih.gov
  2. Probiotics · ods.od.nih.gov
  3. Reinforcing gut integrity: A systematic review and meta-analysis of clinical trials assessing probiotics, synbiotics, and prebiotics on intestinal permeability markers · pubmed.ncbi.nlm.nih.gov
  4. Effect of Probiotic Supplementation on Intestinal Permeability in Overweight and Obesity: A Systematic Review of Randomized Controlled Trials and Animal Studies · pubmed.ncbi.nlm.nih.gov
  5. Probiotics in Health Care: A Critical Appraisal · annualreviews.org
  6. UCC118 supplementation reduces exercise-induced gastrointestinal permeability and remodels the gut microbiome in healthy humans · pubmed.ncbi.nlm.nih.gov
  7. Clinical Response and Changes of Cytokines and Zonulin Levels in Patients with Diarrhoea-Predominant Irritable Bowel Syndrome Treated with Bifidobacterium Longum ES1 for 8 or 12 Weeks: A Preliminary Report · pmc.ncbi.nlm.nih.gov
  8. Clinical Response and Changes of Cytokines and Zonulin Levels in Patients with Diarrhoea-Predominant Irritable Bowel Syndrome Treated with Bifidobacterium Longum ES1 for 8 or 12 Weeks: A Preliminary Report · pubmed.ncbi.nlm.nih.gov
  9. Probiotic Bifidobacterium bifidum BGN4 supplementation modulates gut microbiome composition and reduces circulating zonulin, TNFα, and insulin in adults with excess adiposity: a randomized, double-blind, placebo-controlled trial. · pubmed.ncbi.nlm.nih.gov
  10. A Novel Combination of Probiotic Supplements Reduces Gut Permeability, Oxidative Stress, and Inflammation in Undernourished Adults: A Randomized Controlled Trial · pmc.ncbi.nlm.nih.gov
  11. A Novel Combination of Probiotic Supplements Reduces Gut Permeability, Oxidative Stress, and Inflammation in Undernourished Adults: A Randomized Controlled Trial - Ahmadi‐Khorram - 2026 - Food Science & Nutrition · onlinelibrary.wiley.com
  12. Efficacy and Safety of a Probiotic Containing Saccharomyces boulardii CNCM I-745 in the Treatment of Small Intestinal Bacterial Overgrowth in Decompensated Cirrhosis: Randomized, Placebo-Controlled Study · pmc.ncbi.nlm.nih.gov
  13. Saccharomyces boulardii CNCM I-745 on Intestinal Barrier Function · mayo.edu

Queries

3 queries · click a column to sort
Query / typeSearchIntentQuery classRouting formatClusterFreq ↓Weight
human clinical trials probiotic strains intestinal permeability lactulose mannitol randomized trial Lactobacillus rhamnosus GG Bifidobacterium infantis 35624
OBSERVED
Google ↗
AI Mode ↗
—Reason——1x
of 1
probiotic intestinal barrier permeability clinical trial strain-specific evidence review 2024 2025
OBSERVED
Google ↗
AI Mode ↗
—Reason——1x
of 1
probiotic supplements strain labels Align 35624 Culturelle LGG Florastor CNCM I-745 Visbiome strains
OBSERVED
Google ↗
AI Mode ↗
—Comparison——1x
of 1