Are prescription tretinoin micro gels less irritating for mature skin than traditional cream formulas when comparing them for reducing deep sun damage and fine lines?
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Fan-out diagram
The searches the AI actually ran for this prompt.
SEED QUERY
Are prescription tretinoin micro gels less irritating for mature skin than traditional cream formulas when comparing them for reducing deep sun damage and fine lines?
3 real searches · 1 real-search pass
tretinoin microsphere gel versus cream irritation photoaging randomized trial mature skin fine wrinkles photodamageGoogle ↗
OBSERVEDConsequence
tretinoin cream photoaging fine wrinkles solar damage clinical evidence microsphere gel formulation irritation reviewGoogle ↗
OBSERVEDConsequence
tretinoin microsphere gel prescribing information irritation controlled release vehicle creamGoogle ↗
OBSERVEDOther / navigational
Badge and edge weight = share of passes that produced the query. Hover a query for its intent and routing format.
Query classes
Google's semantic query class for every sub-query: what kind of answer each search is after, simulated vs real.
ChatGPT real searches (3)
Classes come from the query-classifier (a local Laya model). 2 of 3 calls are low-confidence (under 50%) — hover a query in the table to see its confidence.
Searches and sources
ChatGPT3 real searches · gpt-6
tretinoin microsphere gel versus cream irritation photoaging randomized trial mature skin fine wrinkles photodamage Google ↗
tretinoin cream photoaging fine wrinkles solar damage clinical evidence microsphere gel formulation irritation review Google ↗
tretinoin microsphere gel prescribing information irritation controlled release vehicle cream Google ↗
- DailyMed · dailymed.nlm.nih.gov
- label · accessdata.fda.gov
- Tretinoin microsphere gel 0.1% for photodamaged facial skin: a placebo-controlled trial · pubmed.ncbi.nlm.nih.gov
- Long-term efficacy and safety of tretinoin emollient cream 0.05% in the treatment of photodamaged facial skin: a two-year, randomized, placebo-controlled trial. · pubmed.ncbi.nlm.nih.gov
- Two concentrations of topical tretinoin (retinoic acid) cause similar improvement of photoaging but different degrees of irritation. A double-blind, vehicle-controlled comparison of 0.1% and 0.025% tretinoin creams · pubmed.ncbi.nlm.nih.gov
Queries
3 queries · click a column to sort
| Query / type | Search | Intent | Query class | Routing format | Cluster | Freq ↓ | Weight |
|---|---|---|---|---|---|---|---|
tretinoin microsphere gel versus cream irritation photoaging randomized trial mature skin fine wrinkles photodamage OBSERVED | Google ↗ AI Mode ↗ | — | Consequence | — | — | 1x of 1 | |
tretinoin cream photoaging fine wrinkles solar damage clinical evidence microsphere gel formulation irritation review OBSERVED | Google ↗ AI Mode ↗ | — | Consequence | — | — | 1x of 1 | |
tretinoin microsphere gel prescribing information irritation controlled release vehicle cream OBSERVED | Google ↗ AI Mode ↗ | — | Other / navigational | — | — | 1x of 1 |