Real ChatGPT answer · index seedPp6ZP2GxkU4completeFood and restaurants · healthy eatinginformational

How do sugar substitutes like aspartame and acesulfame potassium impact insulin sensitivity and systemic inflammation in long term users?

ChatGPTgpt-62 queries11/1/2026
Download run

Fan-out diagram

The searches the AI actually ran for this prompt.

SEED QUERY
How do sugar substitutes like aspartame and acesulfame potassium impact insulin sensitivity and systemic inflammation in long term users?
2 real searches · 1 real-search pass
long-term aspartame acesulfame potassium insulin sensitivity inflammation human studies systematic review randomized trials 2024 2025Google ↗
OBSERVED
non-sugar sweeteners gut microbiome insulin sensitivity inflammation aspartame acesulfame potassium human evidence reviewGoogle ↗
OBSERVED

Badge and edge weight = share of passes that produced the query. Hover a query for its intent and routing format.

Query classes

Google's semantic query class for every sub-query: what kind of answer each search is after, simulated vs real.

Classifying 2 queries…

Searches and sources

ChatGPT2 real searches · gpt-6
long-term aspartame acesulfame potassium insulin sensitivity inflammation human studies systematic review randomized trials 2024 2025 Google ↗
non-sugar sweeteners gut microbiome insulin sensitivity inflammation aspartame acesulfame potassium human evidence review Google ↗
  1. The Effects of Aspartame on Glucose, Insulin, and Appetite-Regulating Hormone Responses in Humans: Systematic Review and Meta-Analyses · pmc.ncbi.nlm.nih.gov
  2. The Effects of Aspartame on Glucose, Insulin, and Appetite-Regulating Hormone Responses in Humans: Systematic Review and Meta-Analyses · advances.nutrition.org
  3. Consumption of a Carbonated Beverage with High-Intensity Sweeteners Has No Effect on Insulin Sensitivity and Secretion in Nondiabetic Adults · pubmed.ncbi.nlm.nih.gov
  4. Consumption of a Carbonated Beverage with High-Intensity Sweeteners Has No Effect on Insulin Sensitivity and Secretion in Nondiabetic Adults · jn.nutrition.org
  5. The effect of regular consumption of four low- or no-calorie sweeteners on glycemic response in healthy women: A randomized controlled trial · pubmed.ncbi.nlm.nih.gov
  6. The effect of regular consumption of four low- or no-calorie sweeteners on glycemic response in healthy women: A randomized controlled trial · sciencedirect.com
  7. Effect of low-and non-calorie sweeteners on the gut microbiota: A review of clinical trials and cross-sectional studies · pubmed.ncbi.nlm.nih.gov
  8. Consumption of Diet Soda Sweetened with Sucralose and Acesulfame-Potassium Alters Inflammatory Transcriptome Pathways in Females with Overweight and Obesity · pubmed.ncbi.nlm.nih.gov
  9. Nonnutritive Sweetener Consumption, Metabolic Risk Factors, and Inflammatory Biomarkers Among Adults in the Cancer Prevention Study-3 Diet Assessment Sub-Study · pubmed.ncbi.nlm.nih.gov
  10. Nonnutritive Sweetener Consumption, Metabolic Risk Factors, and Inflammatory Biomarkers Among Adults in the Cancer Prevention Study-3 Diet Assessment Sub-Study · jn.nutrition.org
  11. Nonnutritive Sweetener Consumption, Metabolic Risk Factors, and Inflammatory Biomarkers Among Adults in the Cancer Prevention Study-3 Diet Assessment Sub-Study · jn.nutrition.org
  12. Association between intake of non-sugar sweeteners and health outcomes: systematic review and meta-analyses of randomised and non-randomised controlled trials and observational studies · bmj.com
  13. Artificial and Other Non-Nutritive Sweeteners, the Microbiome, and Cardiometabolic Health. · pubmed.ncbi.nlm.nih.gov

Queries

2 queries · click a column to sort
Query / typeSearchIntentQuery classRouting formatClusterFreq ↓Weight
long-term aspartame acesulfame potassium insulin sensitivity inflammation human studies systematic review randomized trials 2024 2025
OBSERVED
Google ↗
AI Mode ↗
————1x
of 1
non-sugar sweeteners gut microbiome insulin sensitivity inflammation aspartame acesulfame potassium human evidence review
OBSERVED
Google ↗
AI Mode ↗
————1x
of 1