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Is berberine actually as effective as low dose rosuvastatin for lowering LDL cholesterol in patients with statin intolerance?

ChatGPTgpt-62 queries11/1/2026
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The searches the AI actually ran for this prompt.

SEED QUERY
Is berberine actually as effective as low dose rosuvastatin for lowering LDL cholesterol in patients with statin intolerance?
2 real searches · 1 real-search pass
berberine LDL cholesterol randomized trial meta-analysis statin intolerance rosuvastatin low dose comparisonGoogle ↗
OBSERVED
rosuvastatin 5 mg LDL reduction dose response statin intolerance guidelines nonstatin therapy berberine cardiovascular outcomesGoogle ↗
OBSERVED

Badge and edge weight = share of passes that produced the query. Hover a query for its intent and routing format.

Query classes

Google's semantic query class for every sub-query: what kind of answer each search is after, simulated vs real.

Classifying 2 queries…

Searches and sources

ChatGPT2 real searches · gpt-6
berberine LDL cholesterol randomized trial meta-analysis statin intolerance rosuvastatin low dose comparison Google ↗
rosuvastatin 5 mg LDL reduction dose response statin intolerance guidelines nonstatin therapy berberine cardiovascular outcomes Google ↗
  1. Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials. · pubmed.ncbi.nlm.nih.gov
  2. 2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines · ahajournals.org
  3. The effects of berberine supplementation on cardiovascular risk factors in adults: A systematic review and dose-response meta-analysis · pmc.ncbi.nlm.nih.gov
  4. Low-density lipoprotein-cholesterol lowering effect of a nutraceutical regimen with or without ezetimibe in hypercholesterolaemic patients with statin intolerance · pubmed.ncbi.nlm.nih.gov
  5. Low-density lipoprotein-cholesterol lowering effect of a nutraceutical regimen with or without ezetimibe in hypercholesterolaemic patients with statin intolerance · pmc.ncbi.nlm.nih.gov
  6. 2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines · doi.org
  7. 2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines · doi.org
  8. 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2026 | Diabetes Care · doi.org
  9. 2022 ACC Expert Consensus Decision Pathway on the Role of Nonstatin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk: A Report of the American College of Cardiology Solution Set Oversight Committee · jacc.org

Queries

2 queries · click a column to sort
Query / typeSearchIntentQuery classRouting formatClusterFreq ↓Weight
berberine LDL cholesterol randomized trial meta-analysis statin intolerance rosuvastatin low dose comparison
OBSERVED
Google ↗
AI Mode ↗
————1x
of 1
rosuvastatin 5 mg LDL reduction dose response statin intolerance guidelines nonstatin therapy berberine cardiovascular outcomes
OBSERVED
Google ↗
AI Mode ↗
————1x
of 1