Review the clinical efficacy of Epi-On versus Epi-Off corneal collagen cross-linking for progressive keratoconus in terms of halting progression and visual recovery speed.
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The searches the AI actually ran for this prompt.
SEED QUERY
Review the clinical efficacy of Epi-On versus Epi-Off corneal collagen cross-linking for progressive keratoconus in terms of halting progression and visual recovery speed.
3 real searches · 1 real-search pass
epithelium-on versus epithelium-off corneal cross-linking keratoconus randomized trials meta-analysis progression Kmax visual acuity 2024Google ↗
OBSERVEDConsequence
Cochrane transepithelial versus epithelium-off corneal cross-linking keratoconus reviewGoogle ↗
OBSERVEDReason
FDA Photrexa KXL epithelium off progressive keratoconus trial 5 year outcomesGoogle ↗
OBSERVEDReason
Badge and edge weight = share of passes that produced the query. Hover a query for its intent and routing format.
Query classes
Google's semantic query class for every sub-query: what kind of answer each search is after, simulated vs real.
ChatGPT real searches (3)
Classes come from the query-classifier (a local Laya model). 2 of 3 calls are low-confidence (under 50%) — hover a query in the table to see its confidence.
Searches and sources
ChatGPT3 real searches · gpt-6
epithelium-on versus epithelium-off corneal cross-linking keratoconus randomized trials meta-analysis progression Kmax visual acuity 2024 Google ↗
Cochrane transepithelial versus epithelium-off corneal cross-linking keratoconus review Google ↗
FDA Photrexa KXL epithelium off progressive keratoconus trial 5 year outcomes Google ↗
- Corneal collagen cross-linking epithelium-on vs. epithelium-off: a systematic review and meta-analysis. · pubmed.ncbi.nlm.nih.gov
- Epithelium-on versus epithelium-off corneal collagen crosslinking for keratoconus: a systematic review and meta-analysis · pmc.ncbi.nlm.nih.gov
- Efficacy and Safety of Epi-On vs Epi-Off Corneal Cross-Linking in Corneal Ectasia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials · pubmed.ncbi.nlm.nih.gov
- A Systematic Review and Meta-Analysis Comparing Epithelium-On and Epithelium-Off Corneal Collagen Cross-Linking in Keratoconus Management: Integrating New Evidence · pubmed.ncbi.nlm.nih.gov
- Transepithelial versus epithelium-off corneal cross-linking for the treatment of progressive keratoconus: a randomized controlled trial · pubmed.ncbi.nlm.nih.gov
- Transepithelial versus Epithelium-off Corneal Collagen Cross-linking for Corneal Ectasia: A Systematic Review and Meta-analysis · pubmed.ncbi.nlm.nih.gov
- Full article: Evidence-Based Clinical Practice Guideline for Diagnosis, Treatment, and Follow-Up of Keratoconus Patients · tandfonline.com
Queries
3 queries · click a column to sort
| Query / type | Search | Intent | Query class | Routing format | Cluster | Freq ↓ | Weight |
|---|---|---|---|---|---|---|---|
epithelium-on versus epithelium-off corneal cross-linking keratoconus randomized trials meta-analysis progression Kmax visual acuity 2024 OBSERVED | Google ↗ AI Mode ↗ | — | Consequence | — | — | 1x of 1 | |
Cochrane transepithelial versus epithelium-off corneal cross-linking keratoconus review OBSERVED | Google ↗ AI Mode ↗ | — | Reason | — | — | 1x of 1 | |
FDA Photrexa KXL epithelium off progressive keratoconus trial 5 year outcomes OBSERVED | Google ↗ AI Mode ↗ | — | Reason | — | — | 1x of 1 |